Vaccine-boosted CAR T crosstalk with host immunity to reject tumors with antigen heterogeneity

antigen heterogeneity 가진 tumors를 거부하는 host immunity 함께 Vaccine-boosted CAR T crosstalk. Abstract Chimeric antigen receptor (CAR) T cell therapy는 인간 암을 효과적으로 치료하지만, CAR가 인식하는 loss of the antigen은…

Continue ReadingVaccine-boosted CAR T crosstalk with host immunity to reject tumors with antigen heterogeneity

SLC38A2 and glutamine signalling in cDC1s dictate anti-tumour immunity

cDC1의 SLC38A2 및 glutamine signalling이 anti-tumour immunity 결정합니다. Abstract Cancer cells은 그 메커니즘이 잘 알려져 있지 않은 tumour–immune interactions을 통해 T cell-mediated killing을 회피합니다. Dendritic cells (DC), 특히 type-1 conventional…

Continue ReadingSLC38A2 and glutamine signalling in cDC1s dictate anti-tumour immunity